Studies on the Barbituric Acid Derivatives. II
نویسندگان
چکیده
منابع مشابه
Parahydrogen induced polarization of barbituric acid derivatives: 1H hyperpolarization studies.
Homogeneous hydrogenation of barbituric acid derivatives with parahydrogen yields a substantial increase of the (1)H NMR signals of the reaction products. These physiologically relevant compounds were hydrogenated at both ambient and elevated temperatures and pressures using a standard cationic rhodium catalyst. The resulting nonthermal nuclear spin polarization (hyperpolarization) is limited b...
متن کاملSynthesis and dynamics studies of barbituric acid derivatives as urease inhibitors
BACKGROUND Discovery of potent inhibitors of urease (jack bean) enzyme is the first step in the development of drugs against diseases caused by ureolytic enzyme. RESULTS Thirty-two derivatives of barbituric acid as zwitterionic adducts of diethyl ammonium salts were synthesized. All synthesized compounds (4a-z and 5a-s) were screened for their in vitro inhibition potential against urease enzy...
متن کاملHabitual Use of Barbituric Acid Derivatives in India
or luminal (di-phenyl-barbiturie acid), (7) sodium luminal, (8) phanodorn (cyclo-hexenyl-ethyl-barbituric acid), (9) evipan (N. methyl-cyclo-hexenyl-methylbarbituric acid), (10) sodium evipan, (11) pentobarbitone (ethyl-methyl-butyl-barbituric acid) and (12) its sodium salt, nembutal, (13) ipral (calcium ethyl iso-propyl-barbituric acid), (14) allonal (a combination of allyl-iso-propyl-barbitur...
متن کاملGreen Synthesis and Urease Inhibitory Activity of Spiro-pyrimidinethiones/spiro-Pyrimidinones-barbituric Acid Derivatives
Sulfonic acid functionalized SBA-15 (SBA-Pr-SO3H) with pore size 6 nm as an efficient heterogeneous nanoporous solid acid catalyst exhibited good catalytic activity in the Biginelli-like reaction in the synthesis of spiroheterobicyclic rings with good yield and good recyclability. Spiro-pyrimidinethiones/spiro-pyrimidinones-barbituric acid derivatives were synthesized in a simple and efficient ...
متن کاملStudies on the control of pyrimidine biosynthesis in human diploid cell strains. II. Effects of 5-azaorotic acid, barbituric acid, and pyrimidine precursors on cellular phenotype.
Human diploi(l cell strains grown in 6-azauridine (6-AZUR) acquire increased activity for orotidine-.5v'-monophosphate (OM\[P) pyrophosphorylase and OM\P decarboxylase the final two enzymes in the biosynthetic pathway leading to uridine-5'-monophosphate (Ui\JP).1 The elevation of enzyme activity occurs even when the concentration of cytidine in the medium is enough to satisfy completely the req...
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ژورنال
عنوان ژورنال: NIPPON KAGAKU KAISHI
سال: 1935
ISSN: 0369-4208,2185-0909
DOI: 10.1246/nikkashi1921.56.12_1487